Full title

Solution structure of human SRSF2 (SC35) RRM

Authors

• GM Daubner, ETH Zürich, CH
• A Cléry, ETH Zürich, CH
• S Jayne, ETH Zürich, CH
• J Stevenin, Université de Strasbourg, FR
• FHT Allain, ETH Zürich, CH

Published

12 Jul 2024, 3:59 p.m.

Files

10 spectra, 0 peak lists, 0 additional files

Total HDD usage

3.4 GB

Uploaded by

Piotr Klukowski (PiotrKlukowski)

Entry type

Single protein molecule

Molecule identifier

Components

• Polypeptide chain 1
  135 residues
  MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGSMSYGRPPPDVEGMTSL
  KVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKR
  DAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHS

Source organism

Homo sapiens

Expressed in

Escherichia coli BL21(DE3)

PDB ID

2LEA

BMRB ID

17705

Publication

Daubner, G. M., Cléry, A., Jayne, S., Stevenin, J. & Allain, F. H.-T. Asyn-anticonformational difference allows SRSF2 to recognize guanines and cytosines equally well. The EMBO Journal 31, 162–174 (2011).
DOI: 10.1038/emboj.2011.367